Clagold EQ combines NMN 250mg, Urolithin A 200mg, and Oyster Mushroom Extract (L-Ergothioneine) 100mg — a next-generation cellular longevity formula targeting the mitochondrial, mitophagic, and oxidative mechanisms that determine oocyte quality and ovarian reserve.
Clagold EQ is formulated with Nicotinamide Mononucleotide (NMN) 250mg + Urolithin A 200mg + Oyster Mushroom Extract Containing L-Ergothioneine 100mg. These three actives represent a converging approach to ovarian rejuvenation — addressing NAD+ depletion, mitochondrial quality control, and follicular oxidative stress simultaneously. Each component targets a distinct but interrelated mechanism in reproductive cellular biology.
NMN 250mg: Restoring NAD+ in Ageing Oocytes
Nicotinamide Adenine Dinucleotide (NAD+) is the central cofactor for mitochondrial energy metabolism and DNA repair — both critical for oocyte viability. NAD+ levels decline by up to 50% between the ages of 30 and 50, directly corresponding with the decline in oocyte quality and ovarian reserve seen in this period. NMN is a direct precursor to NAD+ and is rapidly converted after absorption. In reproductive biology, restored NAD+ levels activate Sirtuins (SIRT1, SIRT3) that regulate meiotic spindle assembly, chromosomal segregation accuracy, and mitochondrial biogenesis — the core determinants of embryo euploidy.
Urolithin A 200mg: Mitophagy for Mitochondrial Quality Control
Human oocytes contain approximately 100,000 mitochondria per cell — more than any other cell type — because fertilisation, early cleavage, and blastocyst formation rely entirely on maternally inherited mitochondrial ATP. As oocytes age, dysfunctional mitochondria accumulate, generating ROS and reducing the ATP available for spindle formation. Urolithin A is the only known natural compound that robustly activates mitophagy — the selective autophagy of damaged mitochondria. By clearing this dysfunctional mitochondrial load, Urolithin A restores the quality of the mitochondrial pool available to the developing oocyte.
L-Ergothioneine 100mg: Antioxidant Defence in the Follicular Microenvironment
L-Ergothioneine (ERGO) is a naturally occurring amino acid found in high concentrations in Oyster Mushroom extract. Unlike most antioxidants, ERGO has a dedicated transporter (OCTN1) that actively concentrates it within cells under oxidative stress — meaning it is selectively delivered precisely where it is most needed. Follicular fluid ROS — generated by ovarian hyperstimulation, inflammation, and metabolic stress — directly damage oocyte DNA and the zona pellucida. ERGO neutralises these ROS with exceptional specificity, preserving the integrity of the follicular microenvironment throughout folliculogenesis.
- check_circleNMN 250mg: Precursor to NAD+; activates Sirtuins that govern meiotic fidelity and mitochondrial biogenesis
- check_circleUrolithin A 200mg: Induces mitophagy — clears damaged mitochondria to restore oocyte energy quality
- check_circleL-Ergothioneine 100mg: Actively concentrates in cells under oxidative stress via OCTN1 transporter; protects follicular DNA
- check_circleTablet formulation: Once-daily dosing with sustained release for consistent intracellular levels
format_quote"Clagold EQ's combination of NMN, Urolithin A, and L-Ergothioneine addresses ovarian rejuvenation at the cellular level — restoring NAD+, clearing dysfunctional mitochondria, and protecting the follicular environment from oxidative damage. This is what next-generation reproductive nutraceutical science looks like." — Dr. Varsha, Gynaecologist